December 2024: Remote Health with Smart Patches

Wearable tech enables non-invasive, continuous health monitoring, transforming patient care.

Image credits: Linxens

In today's rapidly evolving healthcare landscape, some challenges remain hard to address. Especially when considering access and performance of remote monitoring, which tends to be either expensive or inaccurate. Remote monitoring technologies are emerging as powerful tools for improving patient care and outcomes. Among these, remote electrocardiogram (ECG) and sweat monitoring stand out as particularly promising innovations.

These tools combine innovations in materials, sensing technologies, and industrial processes. Developing a stick-to-skin wearable, also known as electronic skin patch or smart patch, does not require industrial machines only, but creativeness and experience on how to design a patch and assemble layers of different polymers, to obtain a product with very specific features such as comfort, stretchability, breathability or stickiness.

Linxens Healthcare, as a contract design and manufacturing company, started its journey in medical sensors by designing and manufacturing the electrochemical sensors for blood gas monitoring used by Siemens Healthineers in their EPOC system. Since then, the capacity to propose custom design for a diversity of electrochemical sensors has expanded and combined with unique capabilities in stick-to-skin wearables. Today Linxens   offers design support and full manufacturing for stick-to-skin wearables, addressing complex manufacturing challenges through our clinical expertise, especially in ECG patches. Leveraging a deep understanding of market demands and customer requirements, we enhance production efficiency and application performance, delivering exceptional results with time-saving solutions. Our capabilities include screen-printed electrodes, converting and die-cutting, full assembly, and packaging—ensuring a seamless process from design to final product.

Enabling remote health opens the ways to innovative companies to build up their products, while they focus on what to do with the data, Linxens Healthcare focuses on how to collect the data. Many applications in healthcare, and more particularly in the medical sector, benefit today from remote monitoring patches. EEG, fetal monitoring or vital signs are only few of them. And two applications in particular show a fast-growing development:

  • Remote Electrocardiogram (ECG)
  • Sport patches based on sweat monitoring

Remote ECG monitoring offers a non-invasive approach to continuously track a patient's heart rhythm. By leveraging wearable devices and wireless technology, healthcare providers can monitor patients remotely, enabling early detection of potential cardiac issues such as arrhythmias.

  • Early Detection: Continuous monitoring allows for the early identification of irregular heart rhythms, potentially preventing serious complications.
  • Reduced Hospitalizations: Timely intervention, facilitated by remote monitoring, can reduce the need for hospitalization and improve patient quality of life.
  • Enhanced Patient Engagement: Remote monitoring empowers patients to take an active role in their own care, increasing adherence to treatment plans.
  • Data-Driven Insights: The wealth of data generated by remote ECG monitoring enables healthcare providers to analyze trends and make informed decisions about patient management.

Another area requires to combine unique competences in skin patches assembly, microfluidic for sweat collection, and electrochemical sensors for real-time sweat monitoring. Widely used in glucose strip for diabetes for many years, electrochemical sensors are now expanding to other point-of-care testing such as infectious diseases and chronic diseases, or to continuous monitoring, offering accurate measurement at cost.

Sweat monitoring, a relatively new technology, offers a non-invasive method to assess various physiological parameters, including hydration status, electrolyte balance, and stress levels. By analyzing the composition of sweat, healthcare providers can gain valuable insights into a patient's overall health.

  • Real-Time Insights: Sweat monitoring provides real-time feedback on a patient's physiological state during exercise or daily activities.
  • Personalized Health Management: By understanding individual sweat profiles, healthcare providers can offer tailored recommendations for hydration, electrolyte intake, and stress management.
  • Early Warning Signs: Sweat analysis can detect potential health issues like heat stress or dehydration before they escalate.

Combined together, remote ECG and sweat monitoring represent powerful tools for improving access to healthcare, enhancing patient monitoring, and promoting proactive health management.

Linxens Healthcare combines these unique capabilities into a single assembly for sweat collection, incorporating microfluidic channels in a stick-to-skin wearable with microfluidics integrated into the adhesive. This setup also enables simultaneous heart monitoring, making it easier for companies to develop wearables for applications in sports or medical biomolecule analysis.

Linxens Healthcare’s contract manufacturing services aim to enhance and accelerate the development of new solutions for remote monitoring. With over 550 million medical electrochemical sensors supplied and over 30 million medical skin patches delivered, Linxens, with its expertise in flexible materials and medical-grade adhesives, supported by dedicated innovation teams, ensures the delivery of products precisely tailored to the specific requirements of today’s healthcare applications, ensuring optimal performance.

About Linxens Healthcare

Linxens Healthcare leads the way in quality-driven product development in connected health with biosensors, stick-to-skin wearables, and traceability solutions.

Biosensors
Gold electrodes are widely used in electrochemical biosensors and physicochemical sensors due to their high conductivity and biocompatibility. Our electrodes are fully customizable, from design to materials. Our roll-to-roll manufacturing process enables scalability, economy of scale, and reproducibility from batch to batch.

Stick-To-Skin Wearables
We have a strong track record in delivering remote cardiac monitoring patches and other medical-grade patches. We excel in patch design according to usage, in multilayer converting, in screen-printed electrodes as well as in the integration of electrochemical and physicochemical sensors.

Track & Trace solutions
We supply HF and UHF RFID labels for tracing and authenticating consumables used in medical devices and diagnostic instruments. Our services include inlay manufacturing, converting, and RFID performance testing.

Sam Draper
December 1, 2024

December 2024

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